Motorway A14 exit Fano (PU). take the direction of Rome (E78), exit Lucrezia (about 9km). 
Lucrezia take to Cartoceto Cartoceto direction 5. 
At the first traffic lights keep left towards Cartoceto the second traffic light turn right direction Cartocerto 5. 
At the fork, keep right direction cartoceto 5. 
Keep the provincial road 79 until CARTELO Cartoceto. 
The b & b Three Owls On the dresser is the first yellow house on the left (see image below). 
By train, get off at the station served by Trenitalia Fano, take bus 25 and get off at Calcinelli to get a connection with the bus 73 direct to Cartoceto. 

By plane, the nearest airports are Ancona to "Raffaello Sanzio" What 45km Rimini "Federico Fellini" and 55km from Bologna Airport "G. Marconi" to 170 km.